Your first run: what to do at every stop
Choose a character, read the map and make the first combat decisions.
Slay the Spire 2 guides
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Characters
Ironclad: build damage, then make Exhaust work
Early card choices, healing and the cost of shrinking your deck.
Silent: use discard, Shivs and Poison well
Make Sly trigger correctly and avoid a deck that cannot finish fights.
Regent: manage Stars and your Sovereign Blade
Budget two resources and build a repeatable Forge plan.
Necrobinder: keep Osty useful and time Doom
Understand two health bars, Summon and the delayed kill threshold.
Defect: channel the right Orb at the right time
Plan passive effects, Evokes and Glass before adding more slots.
Run planning
Draft better cards and choose safer routes
A practical decision process for rewards, upgrades, shops and elites.
Choose Ancient rewards and enchantments
Evaluate act-start offers against the deck you are already playing.
Shops and rest sites: spend for the next fight
Removal costs by Ascension, a purchase order, and a practical rest-versus-upgrade decision.
Bosses
Vantom and Kaiser Crab: prepare for their mechanics
Use hit counts against Slippery and facing against Surround.
Aeonglass: manage Wither and survive Ebb
A Main-branch preparation guide, with a plan for each character and checks before ending your turn.
Multiplayer
Play co-op with friends and troubleshoot invites
Party size, platform support and a short connection checklist.
Troubleshooting
Slay the Spire 2 progress missing? Check before replacing a save
Check profile and mode, distinguish a lost Timeline Epoch, then use the applicable recovery path with preserved saves.
Updates
Main or Beta: use the right patch guide
Current branch baselines, important changes and what is still coming.
Tool
Draw-odds calculator: will you find the card?
Compare deck size, useful copies and draw count without an account.
Combat
Use potions before a fight gets away from you
Evaluate timing, hand space and immediate value without relying on a universal potion tier list.